Caffeine is the most widely consumed stimulant. Caffeine is known to in-crease energetic metabolism throughout the brain, but it also decreases cerebral blood flow, inducing relative cerebral hypoperfusion. Caffeine ac-tivates norepinephrine neurons and appears to affect the local release of dopamine. Many of the warning effects of caffeine may be related to the action of methylxanthine on serotonin neurons. In this sense, this study aimed to identify the main effects of caffeine on the body. This is a literature review study addressing the main effects of caffeine on the body. In order to select the studies, an online survey of articles has been conducted on sites such as the Scientific Electronic Library Online (SciELO), Medical Literature Analysis and Retrieval System Online (MEDLINE) and Latin American and Caribbean Literature in Health Sciences (LILACS), using the descriptors “caffeine”, “effects of caffeine” and “methylxanthine”. We included the studies published between the years 2000 to 2018, which explicitly contemplate the evaluated aspects. In general, caffeine has effects on anxiety and sleep that vary according to individual sensitivity to methylxanthine. The central nervous system does not appear to develop a great tolerance to the effects of caffeine, although the symptoms of dependence and withdrawal are reported.
Cite this paper
Camargo, M. A. F. and Camargo, C. A. C. M. (2019). Effects of Caffeine on the Organism—Literature Review. Open Access Library Journal, 6, e5265. doi: http://dx.doi.org/10.4236/oalib.1105265.
Galvao, T.F. and Pereira, M.G. (2014) Revisoes sistemáticas da literatura: Passos para asua elaboracao. Epidemiologia e Servicos em Saúde, 23, 183-184.
https://doi.org/10.5123/S1679-49742014000100018
Munoz, S.I.S., Takayanagui, A.M.M., dos Santos, C.B. and Sanchez-Sweatman, O. (2002) Systematic Literature Review and Meta-Analysis: Basic Notions about Its Design, Interpretation and Application in Health Research. Brazilian Nursing Communication Symposium, Sao Paulo, 8 May 2002.
http://www.proceedings.scielo.br/scielo.php?script=sci_arttext&pid=MSC0000000052002000200010&lng=en&nrm=abn
Santos, A.L.P., Santos, C.O., Rosa, N.R., Souza, P. and Mazeto, T.K. (2015) Efeito da cafeína no organismo. Rev. Saberes, Rolim de Moura, 3, 45-52. https://facsaopaulo.edu.br/wp-content/uploads/sites/16/2018/05/ed3especial/5.pdf
Carvalho, J.M., Maia, G.A., Sousa, P.H.M. and Rodrigues, S. (2006) Perfil dos principais componentes em bebidas energéticas: Cafeína, taurina, guaraná e glucoronolactona. Rev Inst Adolfo Lutz, 65, 78-85. http://periodicos.ses.sp.bvs.br/pdf/rial/v65n2/v65n2a02.pdf
Prada, D.M.R. (2010) Café, cafeína vs. Salud. Revisión de los efectos del consumo de café en la salud. Sección artículos de revisión de tema. Universidad y Salud, 12, 156-167. http://www.scielo.org.co/scielo.php?pid=S0124-71072010000100017&script=sci_abstract&tlng=es
Cavalcante, J.W.S., Santos Jr., P.R., Menezes, M.F.F., Marques, H.O., Cavalcante, L.P. and Pacheco, W.S. (2000) Influência da Cafeína no Comportamento da Pressao Arterial e da Agregacao Plaquetária. Arq Bras Cardiol, 75, 97-101.
http://publicacoes.cardiol.br/abc/2000/7502/75020002.pdf
Altimari, L., Melo, J., Trindade, M., Tirapegui, J. and Cyrino, E. (2005) Efeito ergogênico da cafeína na performance em exercícios de média e longa duracao. Revista Portuguesa de Ciências do Desporto, 5, 87-101.
http://www.scielo.mec.pt/pdf/rpcd/v5n1/v5n1a10.pdf
Almeida, D.V.P., Pereira, N.K. and Moreira, D.A.R. (2013) Efeitos Cardiovasculares da Cafeína: Revisao de literatura [Cardiovascular Effects of Caffeine: Literature Review]. Revista Ciências em Saúde, 3.
http://cienciadotreinamento.com.br/wp-content/uploads/2017/12/EFEITOS-CARDIOVASCULARES-DA-CAFE%C3%8DNA-REVIS%C3%83O-DE-LITERATURA.pdf