Objective: Traumatic intracranial
epidural hematoma is considered to be the serious complication of head injury
requiring appropriate evaluation and surgical intervention. Although craniotomy
provides an effective evacuation of the hematoma, there is an insufficient data to support one
particular surgical treatment method. The objective of this study is to address
the effectiveness of Urokinase instillation via single burr hole in different
time interval. Method: Forty two patients with traumatic epidural hematoma,
ranging between 15 and 71 years who meet the inclusion criteria were selected for the
retrospective study. All the patients were surgically treated in the First
Affiliated Hospital of Liaoning Medical University from January 2013 to June
2015. Result: The common complication encountered in this study was headache,
dizziness, fever and re-bleeding. In Group-A, 4 (19%) patients complained of headache, 5 (23.8%) dizziness, 1 (4.7%) fever and
re-bleeding occurred in 2 (9.5%)
patients. In Group-B, 2 (9.5%)
patients complained of headache, 1
(4.7%) dizziness, 1 (4.7%) fever and 1 (4.7%) re-bleeding. Out of forty two patients, 3 (7.1%) patients
encountered re-bleeding and received craniotomy. In this study, Group B demonstrates better outcome than Group
A (P < 0.028). Conclusion: Single burr hole with Urokinase instillation is
safe, feasible and effective technique in the treatment of traumatic epidural
hematoma in selected cases where close regular clinical and radiological
monitoring is possible.
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