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Adenoviruses Type D in Patients with Respiratory Tract Infection Symptoms

DOI: 10.4236/oalib.1103624, PP. 1-10

Subject Areas: Virology, Microbiology

Keywords: Adenovirus Type D, Respiratory Tract Infection, HAdV 8

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Abstract

Different Human Adenoviruses (HAdV) serotypes are associated with epidemic respiratory infections. The aim of this study was to detect HAdV from patients with respiratory symptoms and typing virus circulating in North of IRAN. Four hundred nasopharyngeal aspirate samples were obtained from patients with respiratory symptoms. Clinical data were collected. After DNA extraction, Polymerase Chain Reaction (PCR) was done for conserved Hexon region. Positive PCR products were used for sequencing grouping. 37 cases (9.2%) were positives. Clinical symptoms as cough (73%), body (67/6%), and fever (64/9%) were found in 35 infected patients (94/5%) and two patients (15/5%) had no symptoms. All samples were belonged to HAdV of species D (HAdV-8). Prevalence of respiratory adenovirus infection in our area is consistent with other studies in Iran and ocular type of HAdV8 was the frequent adenovirus serotype circulating in acute respiratory disease in Golestan province.

Cite this paper

Javid, N. , Moradi, A. , Mohebbi, A. , Talkhabifard, M. , Kelishadi, M. and Tabarraei, A. (2017). Adenoviruses Type D in Patients with Respiratory Tract Infection Symptoms. Open Access Library Journal, 4, e3624. doi: http://dx.doi.org/10.4236/oalib.1103624.

References

[1]  Moattari, A., Emami, A., Pirbonyeh, N. and Yaghoobi, R. (2014) Detection of Adenovirus Infection among Children with Acute Respiratory Disease during 2010- 2012 in Shiraz, Iran. Archives of Pediatric Infectious Diseases, 2, e15930.
[2]  Akhil, C., Suresha, P.G., Sabeena, S., Hindol, M. and Arunkumar, G. (2016) Genotyping of Human Adenoviruses Circulating in Southwest India. VirusDisease, 27, 266-270.
https://doi.org/10.1007/s13337-016-0337-5
[3]  Belser, J.A., Rota, P.A. and Tumpey, T.M. (2013) Ocular Tropism of Respiratory Viruses. Microbiology and Molecular Biology Reviews, 77, 144-156.
https://doi.org/10.1128/MMBR.00058-12
[4]  Hong, J.-Y., Lee, H.-J., Piedra, P.A., Choi, E.-H., Park, K.-H., Koh, Y.-Y., et al. (2001) Lower Respiratory Tract Infections Due to Adenovirus in Hospitalized Korean Children: Epidemiology, Clinical Features, and Prognosis. Clinical Infectious Diseases, 32, 1423-1429.
https://doi.org/10.1086/320146
[5]  Belsy, A., Odalys, V., Alexander, P., Clara, S., Angel, G., Grehete, G., et al. (2009) Molecular Characterization of Adenoviral Infections in Cuba: Report of an Unusual Association of Species D Adenoviruses with Different Clinical Syndromes. Archives of Virology, 154, 619-627. https://doi.org/10.1007/s00705-009-0338-4
[6]  Jin, Y., Zhang, R.-F., Xie, Z.-P., Yan, K.-L., Gao, H.-C., Song, J.-R., et al. (2013) Prevalence of Adenovirus in Children with Acute Respiratory Tract Infection in Lanzhou, China. Virology Journal, 10, 271.
https://doi.org/10.1186/1743-422X-10-271
[7]  Xu, W., McDonough, M.C. and Erdman, D.D. (2000) Species-Specific Identification of Human Adenoviruses by a Multiplex PCR Assay. Journal of Clinical Microbiology, 38, 4114-4120.
[8]  Casas, I., Avellon, A., Mosquera, M., Jabado, O., Echevarria, J., Campos, R., et al. (2005) Molecular Identification of Adenoviruses in Clinical Samples by Analyzing a Partial Hexon Genomic Region. Journal of Clinical Microbiology, 43, 6176-6182.
https://doi.org/10.1128/JCM.43.12.6176-6182.2005
[9]  Erdin, B.N., Pas, S.D., Durak, I., Schutten, M. and Sayiner, A.A. (2015) A 5-Year Study of Adenoviruses Causing Conjunctivitis in Izmir, Turkey. Journal of Medical Virology, 87, 472-477.
https://doi.org/10.1002/jmv.24071
[10]  Demian, P.N., Horton, K.C., Kajon, A., Siam, R., Hasanin, A.M.N., Sheta, A.E., et al. (2014) Molecular Identification of Adenoviruses Associated with Respiratory Infection in Egypt from 2003 to 2010. BMC Infectious Diseases, 14, 50.
https://doi.org/10.1186/1471-2334-14-50
[11]  Marinheiro, J.C., Sanalios, R.B., dos Santos, C., Alves da Costa, C. and Hársi, C.M. (2009) Duplex-PCR Assay for the Detection of Adenovirus and Respiratory Syncytial Virus in Nasopharyngeal Samples. Memórias do Instituto Oswaldo Cruz, 104, 118-120.
https://doi.org/10.1590/S0074-02762009000100018
[12]  Osiowy, C. (1998) Direct Detection of Respiratory Syncytial Virus, Parainfluenza Virus, and Adenovirus in Clinical Respiratory Specimens by A Multiplex Reverse Transcription-PCR Assay. Journal of Clinical Microbiology, 36, 3149-3154.
[13]  Lee, J.A., Kim, N.H., Kim, S.J., Choi, E.H. and Lee, H.J. (2005) Rapid Identification of Human Adenovirus Types 3 and 7 from Respiratory Specimens via Multiplex Type-Specific PCR. Journal of Clinical Microbiology, 43, 5509-5514.
https://doi.org/10.1128/JCM.43.11.5509-5514.2005
[14]  Echavarria, M., Sanchez, J.L., Kolavic-Gray, S.A., Polyak, C.S., Mitchell-Raymundo, F., Innis, B.L., et al. (2003) Rapid Detection of Adenovirus in Throat Swab Specimens by PCR during Respiratory Disease Outbreaks among Military Recruits. Journal of Clinical Microbiology, 41, 810-812.
https://doi.org/10.1128/JCM.41.2.810-812.2003
[15]  Malekshahi, S.S., Azad, T.M., Yavarian, J., Shahmahmoodi, S., Naseri, M. and Rezaei, F. (2010) Molecular Detection of Respiratory Viruses in Clinical Specimens from Children with Acute Respiratory Disease in Iran. The Pediatric Infectious Disease Journal, 29, 931-933.
[16]  Kahbazi, M., Fahmizad, A., Armin, S., Ghanaee, R., Fallah, F., Shiva, F., et al. (2011) Aetiology of Upper Respiratory Tract Infections in Children in Arak City: A Community Based Study. Acta Microbiologica et Immunologica Hungarica, 58, 289-296.
https://doi.org/10.1556/AMicr.58.2011.4.5
[17]  Luiz, L.N., Leite, J.P.G., Yokosawa, J., Carneiro, B.M., Pereira Filho, E., et al. (2010) Molecular Characterization of Adenoviruses from Children Presenting with Acute Respiratory Disease in Uberlandia, Minas Gerais, Brazil, and Detection of an Isolate Genetically Related to Feline Adenovirus. Memórias do Instituto Oswaldo Cruz, 105, 712-716. https://doi.org/10.1590/S0074-02762010000500019
[18]  Yeung, R., Eshaghi, A., Lombos, E., Blair, J., Mazzulli, T., Burton, L., et al. (2009) Characterization of Culture-Positive Adenovirus Serotypes from Respiratory Specimens in Toronto, Ontario, Canada: September 2007-June 2008. Virology Journal, 6, 11.
https://doi.org/10.1186/1743-422X-6-11
[19]  Ryan, M.A., Gray, G.C., Smith, B., McKeehan, J.A., Hawksworth, A.W. and Malasig, M.D. (2002) Large Epidemic of Respiratory Illness Due to Adenovirus Types 7 and 3 in Healthy Young Adults. Clinical Infectious Diseases, 34, 577-582.
https://doi.org/10.1086/338471
[20]  Hsieh, W.-Y., Chiu, N.-C., Chi, H., Huang, F.-Y. and Hung, C.-C. (2009) Respiratory Adenoviral Infections in Taiwanese Children: A Hospital-Based Study. Journal of Microbiology, Immunology, and Infection, 42, 371-377.
[21]  Tate, J.E., Bunning, M.L., Lott, L., Lu, X., Su, J., Metzgar, D., et al. (2009) Outbreak of Severe Respiratory Disease Associated with Emergent Human Adenovirus Serotype 14 at a US Air Force Training Facility in 2007. Journal of Infectious Diseases, 199, 1419-1426.
https://doi.org/10.1086/598520
[22]  Hall, C.B., Douglas, R., Schnabel, K.C. and Geiman, J.M. (1981) Infectivity of Respiratory Syncytial Virus by Various Routes of Inoculation. Infection and Immunity, 33, 779-783.

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